Abstract
INTRODUCTION: To date, there remains an urgent need to identify clinical data that can serve as valid criteria for diagnosing sepsis in children, applicable both in global settings and in situations reflecting different clinical situations. In 2024 society critical care medicine USA experts presented the Phoenix Score Sepsis scale for this purpose. OBJECTIVE: A comparative assessment of the discriminatory ability of the Pediatric Sequential Organ Failure Assessment (pSOFA) и Pediatric Logistic Organ Dysfunction (PELOD) 2 and Phoenix Sepsis Score scales for sepsis in children in the healthcare t of the Russian Federation. MATERIALS AND METHODS: Study design: retrospective, observational, multicenter. Inclusion criteria: children over 9 months of age. under 17 years of age who have been diagnosed with septic shock. The end point of the study was 28-day mortality. Demographic and clinical data are presented as median values with interquartile ranges of means and standard deviations. Continuous variables were compared using the Mann-Whitney U test. The discriminatory power of the scales was determined by calculating the area under the receiver operating characteristic curve. RESULTS: In the first 24 hours of hospitalization, the prognosis of survival in children with sepsis was comparable for the scales studied. None of the scoring systems were able to predict disease outcomes in shock. CONCLUSIONS: Our studies have shown that in Russian conditions the information value of the Phoenix Sepsis Score scale is comparable to the pSOFA and PELOD 2 scales. Therefore, it seems rational to use all these scales, although the Phoenix Score Sepsis system must still undergo additional external international validation in countries with limited funding.
Publisher
Practical Medicine Publishing House