Bispecific Antibodies in Clinical Practice and Clinical Trials (Literature Review)-Reference-Cited by-同舟云学术

Bispecific Antibodies in Clinical Practice and Clinical Trials (Literature Review)

Published:2019 Issue:2 Volume:12 Page:25-44
ISSN:1997-6933
Container-title:Clinical oncohematology
language:
Short-container-title:Клиническая онкогематология

Author:

Solopova O.N.¹,Misyurin Vsevolod Andreevich¹^ORCID

Affiliation:

1. NN Blokhin National Medical Cancer Research Center

Abstract

Therapeutic monoclonal antibodies have long been an effective tool deployed by physicians of different specialties, particularly by oncologists. Bispecific antibodies opened up new horizons in the treatment of cancer as they allow to involve a patient’s endogenous immunity in his or her fight against tumor. The present review covers all the formats and strategies used in engineering of bispecific antibodies which reached the stage of clinical trials and also focuses on the available results of these clinical trials.

Publisher

Practical Medicine Publishing House

Subject

Oncology,Hematology

Reference107 articles.

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