Chronic Lymphocytic Leukemia in Blood Relatives: Two Case Reports of Male Siblings-Reference-Cited by-同舟云学术

Chronic Lymphocytic Leukemia in Blood Relatives: Two Case Reports of Male Siblings

Published:2021 Issue:1 Volume:14 Page:69-72
ISSN:1997-6933
Container-title:Clinical oncohematology
language:
Short-container-title:Клиническая онкогематология

Author:

Kurkina Nadezhda Viktorovna¹²,Repina E.A.¹

Affiliation:

1. NP Ogarev National Research Mordovia State University

2. Republican Clinical Hospital No. 4

Abstract

In recent years there are more and more evidences for a hereditary factor in malignant lymphoproliferative disorders. Various lymphoid tumors are diagnosed in blood relatives. This is most frequently observed in chronic lymphocytic leukemia: 13.3 % vs. 8.8 % in non-Hodgkin’s lymphoma and 5.9 % in Hodgkin’s lymphoma. This paper presents two case reports of chronic lymphocytic leukemia in blood relatives (male siblings). Besides, in one of them the efficacy of targeted therapy with ibrutinib is estimated.

Publisher

Practical Medicine Publishing House

Subject

Oncology,Hematology

Reference11 articles.

1. Zenz T, Gribben JG, Hallek M, et al. Risk categories and refractory CLL in the era of chemoimmunotherapy. B I ood. 2012;119(18):4101-7. doi: 10.1182/blood-2011-11-312421.

2. Никитин Е.А., Судариков А.Б. Хронический лимфолейкоз высокого риска: история, определение, диагностика и лечение. Клиническая онкогематология. 2013;6(1):59-67.

3. Богданов А.Н., Кулибаба Т.Г. Острые и хронические лейкозы: учебное пособие. СПб.: Изд-во Санкт-Петербургского университета, 2019. 116 с

4. Клиническая гематология. Под ред. Шт. Берчану. М.: Медицинское издательство, 1985. 1224 с

5. Лейкозы у детей: Клиническое пособие. Под ред. Г.Л. Менткевич, С.А. Маяковой. М.: Практическая медицина, 2009. 384 с