Monoclonal Antibodies: from Development to Clinical Application-Reference-Cited by-同舟云学术

Monoclonal Antibodies: from Development to Clinical Application

Published:2016 Issue:3 Volume:9 Page:237-244
ISSN:1997-6933
Container-title:Clinical oncohematology
language:
Short-container-title:Клиническая онкогематология

Author:

Budchanov Yurii Ivanovich¹

Affiliation:

1. Tver’ Medical University

Abstract

The development of monoclonal antibodies (MABs) resulted in revolutionary achievements in diagnosing and treating of oncohematological disorders. The review dwells on the history of the development and improved technologies for production of monoclonal antibodies illustrated by anti-CD20-MABs which recognize different epitopes of the CD20 antigens and have a higher antitumor activity. Engineering techniques can contribute to understanding the effector mechanisms of the application of the novel anti-CD20-MABs and are intended for further improvement of the treatment results.

Publisher

Practical Medicine Publishing House

Subject

Oncology,Hematology

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