Metabolic screening and metabolomics analysis in the Intellectual Developmental Disorders Mexico Study-Reference-Cited by-同舟云学术

Metabolic screening and metabolomics analysis in the Intellectual Developmental Disorders Mexico Study

Published:2017-07-25 Issue:4, jul-ago Volume:59 Page:423
ISSN:1606-7916
Container-title:Salud Pública de México
language:
Short-container-title:Salud Publica Mex

Author:

Ibarra-González Isabel,Rodríguez-Valentín Rocío,Lazcano-Ponce Eduardo,Vela-Amieva Marcela

Abstract

Objective. Inborn errors of metabolism (IEM) are genetic conditions that are sometimes associated with intellectual developmental disorders (IDD). The aim of this study is to contribute to the metabolic characterization of IDD of unknown etiology in Mexico. Materials and methods. Metabolic screening using tandem mass spectrometry and fluorometry will be performed to rule out IEM. In addition,target metabolomic analysis will be done to characterize the metabolomic profile of patients with IDD. Conclusion. Identification of new metabolomic profiles associated withIDD of unknown etiology and comorbidities will contribute to the development of novel diagnostic and therapeutic schemes for the prevention and treatment of IDD in Mexico.

Publisher

Instituto Nacional de Salud Publica

Subject

Public Health, Environmental and Occupational Health,Public Health, Environmental and Occupational Health

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