Design, synthesis and biological evaluation of 4-piperidin-4-yl-triazole derivatives as novel histone deacetylase inhibitors
Author:
Affiliation:
1. Department of Medicinal Chemistry, School of Pharmacy, Qingdao University
2. Department of Pharmacology, School of Pharmacy, Qingdao University
3. Department of Pharmacology, College of Basic Medicine, Qingdao University
Publisher
International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine,Health (social science)
Link
https://www.jstage.jst.go.jp/article/bst/13/2/13_2019.01055/_pdf
Reference31 articles.
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2. 2. de Ruijter AJ, van Gennip AH, Caron HN, Kemp S, van Kuilenburg AB. Histone deacetylases (HDACs): characterization of the classical HDAC family. Biochem J. 2003; 370:737-749.
3. 3. Gregoretti IV, Lee YM, Goodson HV. Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis. J Mol Biol. 2004; 338:17-31.
4. 4. Kalin JH, Bergman JA. Development and therapeutic implications of selective histone deacetylase 6 inhibitors. J Med Chem. 2013; 56:6297-6313.
5. 5. Falkenberg KJ, Johnstone RW. Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders. Nat Rev Drug Discov. 2014; 13:673-691.
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