Epigenetic modification of <i>Kiss1</i> gene expression in the AVPV is essential for female reproductive aging
Author:
Affiliation:
1. Hospital of Obstetrics and Gynecology, Fudan University, Shanghai, China.
2. Department of Urology, Zhongshan Hospital of Fudan University, Shanghai, China.
3. The Academy of Integrative Medicine of Fudan University, Shanghai, China.
Publisher
International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine,Health (social science)
Link
https://www.jstage.jst.go.jp/article/bst/16/5/16_2022.01358/_pdf
Reference61 articles.
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2. 2. Kauffman AS, Sun Y, Kim J, Khan AR, Shu J, Neal-Perry G.Vasoactive intestinal peptide modulation of the steroid-induced LH surge involves kisspeptin signaling in young but not in middle-aged female rats. Endocrinology. 2014; 155:2222-2232.
3. 3. Xie Q, Kang Y, Zhang C, Xie Y, Wang C, Liu J, Yu C, Zhao H, Huang D. The role of kisspeptin in the control of the hypothalamic-pituitary-gonadal axis and reproduction. Front Endocrinol (Lausanne). 2022; 13:925206.
4. 4. Austad SN. Sex differences in health and aging: A dialog between the brain and gonad? Geroscience. 2019; 41:267-273.
5. 5. Neal-Perry GS, Zeevalk GD, Santoro NF, Etgen AM. Attenuation of preoptic area glutamate release correlates with reduced luteinizing hormone secretion in middle-aged female rats. Endocrinology. 2005; 146:4331-4339.
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