Nutrition in Critically Ill Children with Acute Kidney Injury on Continuous Kidney Replacement Therapy: An Integrative Review and Clinical Practice Points 2023

Author:

Raina Rupesh12ORCID,Suchan Andrew3ORCID,Sethi Sidharth K4,Soundararajan Anvitha1ORCID,Vitale Victoria S2,Keller Gerri L2,Brown Ann-Marie5ORCID,Davenport Andrew6ORCID,Shih Weiwen V7,Nada Arwa8ORCID,Irving Sharon Y9,Mannemuddhu Sai Sudha1011,Crugnale Aylin S1,Myneni Archana1ORCID,Berry Katarina G9,Zieg Jakub12,Alhasan Khalid13,Guzzo Isabella14,Lussier Natalie H2,Yap Hui Kim15,Bunchman Timothy E16

Affiliation:

1. Akron Nephrology Associates/Cleveland Clinic Akron General Medical Center, Akron, OH

2. Akron Children’s Hospital, Akron, OH

3. Johns Hopkins Bayview Medical Center, Baltimore, MD

4. Department of Pediatric Nephrology, Kidney Institute, Medanta, The Medicity, Gurgaon, Haryana, India

5. Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia; Nurse Scientist, Children’s Healthcare of Atlanta, Georgia; PICU Nurse Practitioner, ECU Health, Greenville, NC

6. UCL Department of Renal Medicine, Royal Free Hospital, University College London, London, UK

7. Children’s Hospital Colorado, University of Colorado, Section of Pediatric Nephrology, Aurora, CO

8. Department of Pediatrics, Division of Pediatric Nephrology, Le Bonheur Children's & St. Jude Children’s Research Hospitals, University of Tennessee Health Science Center, Memphis, TN.

9. University of Pennsylvania School of Nursing, Philadelphia, PA, and Children’s Hospital of Philadelphia, Philadelphia, PA.

10. Division of Pediatric Nephrology, East Tennessee Children’s Hospital, Knoxville, TN

11. Department of Medicine, University of Tennessee at Knoxville, TN.

12. Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, V Úvalu 84, 15006 Praha 5, Czech Republic

13. Pediatrics Department, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.

14. Division of Nephrology and Dialysis, Department of Pediatrics, Bambino Gesù Children's Hospital and Research Institute, Piazza Sant'Onofrio 4, 00165, Rome, Italy.

15. Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

16. Department of Pediatrics, Childrens Hospital of Richmond, Virginia Commonwealth University, Richmond, VA.

Abstract

Background: Nutrition plays a vital role in the outcome of critically ill children, particularly those with acute kidney injury (AKI). Currently, there are no established guidelines for children with AKI treated with continuous kidney replacement therapy (CKRT). A thorough understanding of the metabolic changes and nutritional challenges in AKI and CKRT is required. Our objective was to create clinical practice points for nutritional assessment and management in critically ill children with AKI receiving CKRT. Methods: PubMed, MEDLINE, Cochrane, and EMBASE databases were searched for articles related to the topic. Expertise of the authors and a consensus of the workgroup were additional sources of data in the article. Available articles on nutrition therapy in pediatric patients receiving CKRT through January 2023. Results: Based on the literature review, the current evidence base was examined by a panel of experts in pediatric nephrology and nutrition. The panel utilized the literature review as well as their expertise to formulate clinical practice points. The modified Delphi method was used to identify and refine clinical practice points. Conclusions: Forty-four clinical practice points are provided on nutrition assessment, determining energy needs, and nutrient intake in children with AKI and on CKRT based on the existing literature and expert opinions of a multidisciplinary panel.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Psychiatry and Mental health,Neuropsychology and Physiological Psychology

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