Author:
Gotsiridze David,Baramidze Ketevan,Chikhladze Tamar,Otarashvili Tamar,Ioramashvili Hilda
Abstract
Sensitive, accurate and efficient Liquid Chromatographic Method is developed for the quantitative determination of Nitrofuran residues in fish samples. It was found that the coefficient of variation for all four test substances of the Nitrofuran group is from 0.03 ìg / ml less than 2%, respectively the detection minimum was considered to be 0.03ìg / ml; 376 nm wavelength is specific for Nitrofurans; For the quantification of nitrofuran residues in a fish sample validation of the developed Liquid Chromatographic Method revealed complete compliance of the method (Guidance for Industry Bioanalytical Method Validation U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) Center for Veterinary Medicine (CVM) May 2001) with the following validation characteristics of the requirements: detection minimum, specificity, accuracy, correctness and linearity.
Publisher
Association For Science (Publications)
Subject
General Earth and Planetary Sciences,General Agricultural and Biological Sciences,General Environmental Science,Geography, Planning and Development,General Social Sciences,General Arts and Humanities,General Earth and Planetary Sciences,Ecology,Geography, Planning and Development,Earth and Planetary Sciences (miscellaneous),General Environmental Science,Environmental Chemistry,Oceanography,General Earth and Planetary Sciences,Ecology,Aquatic Science,Ecology, Evolution, Behavior and Systematics,Law,Sociology and Political Science,Anthropology,Law,Social Sciences (miscellaneous),Law,Social Sciences (miscellaneous),General Social Sciences,Law,Public Administration,Pathology and Forensic Medicine
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