Back pain, postural balance and quality of life in vertebral fragility fractures: a prospective cohort study

Author:

Scaturro Dalila1,Tomasello Sofia2,Mauro Giulia Letizia1

Affiliation:

1. Dpt. Oncology and Stomatological Surgical Disciplines, University of Palermo, PA IT

2. University of Verona, VR IT

Abstract

Osteoporosis is characterized by poor bone quality, reduced bone mass and and increased risk of fragility fractures. Vertebral fragility fracture can result in chronic pain, postural and balance disorders and poor quality of life (QoL). The purpose of this longitudinal cohort study was to assess the effectiveness of two months of rehabilitation in patients with at least two vertebral fragility fractures receiving vitamin D and denosumab. In 28 patients, we studied the following measures of outcome before (T0) and after (T1) an eight-week rehabilitation programme: pain (Numerical Rating Scale), QoL (36-Item Short Form Survey and Mini-Osteoporosis Quality of Life Questionnaire), vertigo (Dizziness Handicap Inventory, Italian version), mobility (Timed-Up and Go, TUG test) and instrumental posturographic assessment (posturography system). At the end of the treatment improvements in pain and QoL were recorded in all the patients. Pain reduction was recorded in patients with more than two vertebral fractures. In addition, functional improvement (TUG test) was found in those with two vertebral fractures. Our results suggest that combined intervention, including anti-osteoporosis drugs (denosumab, vitamin D) and postural rehabilitation, should be proposed to osteoporotic patients with multiple fragility vertebral fractures. KEY WORDS: Osteoporosis, postural balance, pain, quality of life.

Publisher

Medimay Communication

Reference25 articles.

1. 1. Tarantino U, Iolascon G, Cianferotti L, et al. Clinical guidelines for the prevention and treatment of osteoporosis: summary statements and recommendations from the Italian Society for Orthopaedics and Traumatology. J Orthop Traumatol. 2017;18(Suppl 1):3-36. https://doi.org/10.1007/s10195-017-0474-7

2. 2. Hernlund E, Svedbom A, Ivergård M, et al. Osteoporosis in the European Union: medical management, epidemiology and economic burden. A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch Osteoporos. 2013;8(1):136. https://doi.org/10.1007/s11657-013-0136-1

3. 3. Clark EM, Gooberman-Hill R, Peters TJ. Using self-reports of pain and other variables to distinguish between older women with back pain due to vertebral fractures and those with back pain due to degenerative changes. Osteoporos Int. 2016;27(4): 459-67 [published correction appears in Osteoporos Int. 2018;29(6):1475]. https://doi.org/10.1007/s00198-015-3397-2

4. 4. Imai T, Tanaka S, Kawakami K, Miyazaki T, Hagino H, Shiraki M; A-TOP (Adequate Treatment of Osteoporosis) Research Group.. Health state utility values and patient-reported outcomes before and after vertebral and non-vertebral fractures in an osteoporosis clinical trial. Osteoporos. Int. 2017;28(6):1893-901. https://doi.org/10.1007/s00198-017-3966-7

5. 5. Lorbergs AL, Murabito JM, Jarraya M, et al. Thoracic kyphosis and physical function: the Framingham Study. J Am Geriatr Soc. 2017;65(10):2257-64. https://doi.org/10.1111/jgs.15038

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