A Case of Cobra Bite Complicated with Basilar Artery Occlusion

Author:

Yahaya Siti Nasrina Binti1,Khan Abdul Hanif Khan Yusof2,Sankala Hairuddin Achmad3

Affiliation:

1. Department of Emergency and Trauma, Hospital Putrajaya, Putrajaya, Malaysia

2. Department of Neurology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia

3. Department of Radiology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia

Abstract

Snakebite is one of the most common complaints related to wilderness medicine. Venomous snakebite manifestation is divided into local and systemic envenomation. For the Elapidae group, the most feared complication is respiratory muscle paralysis due to neurotransmitter malfunction at the neuromuscular junction level which leads to respiratory insufficiency. However, there is a lack of evidence or case report incidence to suggest that it can potentially associate with the development of stroke disorder. We present a rare case of massive posterior circulation infarct in a middle-aged gentleman following a cobra bite. He was brought to our center few hours later following the bite and antivenom was administered. He improved shortly after receiving it. However, he had an abrupt drop in his conscious level several hours later. Noncontrast-enhanced computed tomography (NCCT) brain was performed immediately, but stroke disorder was excluded prematurely. Repeated NCCT imaging which was done 12 h apart showed massive posterior circulation infarction with hydrocephalus. He succumbed to death 3 days later. Given its rarity, the evolution of his clinical condition warrants clinician’s early suspicion of potential stroke-related complications that can occur following a cobra bite.

Publisher

Medknow

Subject

Emergency Medicine

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3. Snakebite and envenomation management in Malaysia;Ismail;Toxinology: Clinical Toxinology in Asia Pacific and Africa,2015

4. Immunological cross-reactivity and neutralization of the principal toxins of Naja Sumatrana and related cobra venoms by a Thai polyvalent antivenom (neuro polyvalent snake antivenom);Leong;Acta Trop,2015

5. Cranial CT with 64-, 16-, 4- and single-slice CT systems-comparison of image quality and posterior fossa artifacts in routine brain imaging with standard protocols;Ertl-Wagner;Eur Radiol,2008

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