Abstract
An odontogenic cutaneous sinus tract (OCST) is an uncommon finding caused by prolonged periapical inflammation. Patients typically seek treatment from dermatology and ENT clinics due to a lack of intraoral symptoms and the presence of a cutaneous lesion. Misdiagnosis in certain circumstances may result in ineffective treatment. This current article describes four cases of recurrent OCST that were initially misdiagnosed and treated with surgical excision and orally administered antibiotics, without healing. These cases were referred to the endodontic clinic and diagnosed noninvasively using cone-beam computed tomography. The cases were managed by nonsurgical endodontic treatment, followed by dermatologic treatment protocol to prevent scar formation and healing was observed with a 3-year follow-up. These cases emphasize the importance of considering dental infection as a primary etiologic factor in OCST. Referral for dental care management is essential for diagnosis, treatment, and follow-up.