Affiliation:
1. Department of Oral and Maxillofacial Surgery, Army Dental Corps, New Delhi, India
Abstract
Abstract
Rationale:
Submandibular gland epidermoid cyst is extremely rare and malignant transformation into squamous cell carcinoma (SCC) is even rarer. No such case report is published.
Patient Concerns:
A 49-year-old female reported with a large, slowly growing left-sided neck swelling present for two years. Her primary concern was large swelling.
Diagnosis:
Clinical finding, cytology and imaging were suggestive of ‘Epidermoid Cyst of Submandibular Gland’. Intraoperative frozen section and post-operative definitive histopathological examination (HPE) revealed malignant transformation into SCC.
Treatment:
In toto surgical excision was performed. Once the frozen section HPE confirmed transformation into SCC, clearance of 4–6 mm margin and modified supraomohyoid neck dissection was completed.
Outcome:
No sign of recurrence on 1-year postoperative follow-up.
Take-Away Lesson:
This case is unique of its kind without any previous literature report. In case of large and rapidly growing submandibular gland lesion, possibility of malignant transformation should not be overruled.
Reference10 articles.
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2. Epidermoid cyst of submandibular region;Janarthanam;J Oral Maxillofac Pathol,2012
3. Incidental squamous cell carcinoma in an epidermal inclusion cyst: A case report and review of the literature;Frank;Case Rep Dermatol,2018
4. Squamous cell carcinoma arising in an epidermal inclusion cyst;Alkul;Proc (Bayl Univ Med Cent),2022
5. Squamous cell carcinoma arising from an epidermal inclusion cyst: A case report;Ziadi;N Am J Med Sci,2010