Pineal gland germinoma with spinal drop metastases: A case report and review of literature

Author:

Nath Jyotiman1,Roy Partha S.2,Sarma Gautam1,Sarma Biswajit1,Khanikar Duncan2

Affiliation:

1. Department of Radiation Oncology, Dr B. Borooah Cancer Institute, Guwahati, Assam, India

2. Medical Oncology, Dr B. Borooah Cancer Institute, Guwahati, Assam, India

Abstract

ABSTRACT Germ cell tumor of the central nervous system (CNS) is an infrequent entity consisting of only 0.2%–1.7% of all primary CNS tumors. The pineal gland is the commonest location of CNS germinoma. Traditionally, radiotherapy alone has been used to treat localized pineal germinoma, which has delivered a very high cure rate. Spinal drop metastases from pineal germinoma can develop after a long time from diagnosis and primary treatment. Currently, craniospinal irradiation is the standard of care in metastatic pineal germinoma with spinal drop metastases along with systemic chemotherapy. Very few cases of pineal germinoma with spinal drop metastases have been published in the literature. We report a pineal gland germinoma case with spinal drop metastases in an 18-year-old boy and reviewed the published literature.

Publisher

Medknow

Reference28 articles.

1. Pineal gland tumors: A review;Favero;Cancers,2021

2. SIOPE – Brain tumour group consensus guideline on craniospinal target volume delineation for high-precision radiotherapy;Ajithkumar;Radiother Oncol,2018

3. Germinoma of the pineal;its identity with germinoma (seminoma) of the testis;Friedman;Cancer Res,1947

4. Primary extragonadal germinoma of the pineal gland: A case report;Sumitra;Int J Adv Med,2015

5. Intracranial germ-cell tumors: natural history and pathogenesis;Jennings;J Neurosurg,1985

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3