Colorectal cancer and dostarlimab – An episode in discovery to new era of immunotherapy

Author:

Bethineedi Lakshmi Deepak1,Kutikuppala L. V. Simhachalam2,Boppana Sri Harsha3,Kuchana Sai Kiran4,Ponnaganti Sai Venkata Kalyani5

Affiliation:

1. Department of General Surgery, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India

2. Department of General Surgery, Dr. NTR University of Health Sciences, Vijayawada, Andhra Pradesh, India

3. Department of Anaesthesiology, Division of Perioperative Informatics, University of California, San Diego, La Jolla, CA, USA

4. Department of General Surgery, Kakatiya Medical College, Warangal, Telangana, India

5. Department of General Surgery, Rangaraya Medical College, Kakinada, Andhra Pradesh, India

Publisher

Medknow

Subject

Radiology, Nuclear Medicine and imaging,Oncology,General Medicine

Reference5 articles.

1. Global colorectal cancer burden in 2020 and projections to 2040;Xi;Transl Oncol,2021

2. Immune checkpoint blockade therapy in patients with colorectal cancer harboring microsatellite instability/mismatch repair deficiency in 2022;Andre;Am Soc Clin Oncol Educ Book,2022

3. IOLite:Phase 1b trial of doublet/triplet combinations of dostarlimab with niraparib, carboplatin-paclitaxel, with or without bevacizumab in patients with advanced cancer;Yap;J Immunother Cancer,2022

4. PD-1 blockade in mismatch repair-deficient, locally advanced rectal cancer;Cercek;N Engl J Med,2022

5. Blockade of novel immune checkpoints and new therapeutic combinations to boost antitumor immunity;Archilla-Ortega;J Exp Clin Cancer Res,2022

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