The Impact of Urogenital Tract Infectious Bacteria on Male Fertility

Author:

Alzaidi Jawad R.1,Kareem Aqeel A.2

Affiliation:

1. Department of Medical Lab Techniques, Shatrah Technical College, Southern Technical University, Thi-Qar, Iraq

2. Department of Clinical and Laboratory Science, College of Pharmacy, University of Al-Qadisiyah, Thi-Qar, Iraq

Abstract

Abstract Background: Infertile men aged 18 to 40 with urogenital bacterial infections can be assessed for the presence of pus cells in their sperm or urine using direct microscopy, urine culture, and sperm culture techniques. Objectives: To examine the impact of microbial infections on the male genitourinary system and assess the probability of male sterility resulting from these conditions. Materials and Methods: Microorganisms including Escherichia coli, Proteus mirabilis, coagulase-negative Staphylococci, Staphylococcus aureus, and Klebsiella species, as well as Neisseria gonorrhoeae, Pseudomonas aeruginosa, and Enterococcus faecalis, were identified in samples obtained from semen and urine. Results: The correlation (Cor = 0.1) between isolates found in sperm and urine samples was demonstrated. This correlation indicates the potential for infections originating in the urinary tract to migrate to the spermatic tract. Antibiotics such as gentamicin, ciprofloxacin, rifampicin, ceftriaxone (amoxicillin and clavulanic acid), and augmentin have proven effective in treating severe infections. The broad spectrum of activity exhibited by these potent antibiotics underscores their efficacy in addressing various diseases and conditions caused by infections, as evidenced by their effectiveness against isolated pathogens. Among the patients assessed, 37 individuals were diagnosed with azoospermia, representing 28% of the total; 80 patients exhibited oligospermia, constituting 62% of the cohort; while 13 patients demonstrated sperm counts within the normal range, accounting for 10% of the sample. Conclusion: According to the findings of this prospective study, the occurrence of an infection in the male reproductive system should be regarded as a potential contributing feature to male sterility. This revelation enhances the aggregate body of indication that underscores the significance of considering various factors in assessing male infertility.

Publisher

Medknow

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