Managing Pulmonary Edema Following Amlodipine Toxicity using Non-invasive Ventilation: A Case Report

Abstract

Amlodipine is a dihydropyridine calcium channel blocker that is commonly used in the management of hypertension. Its pharmacological properties give it the advantage of being administered as a single daily dose. This has a positive impact on the patient’s compliance. In contrast, amlodipine overdose represents a significant challenge to the treating clinician. Noncardiogenic pulmonary edema is a rare adverse event associated with toxicity of calcium channel blockers, including amlodipine. It is a life-threatening situation that requires a prompt response. Most reported cases in the literature required invasive ventilation. In this case report, we present a young woman with amlodipine toxicity managed using noninvasive mechanical ventilatory support.