Program for Determining the Dosimetric Contribution of Tc-99m Biokinetics in Estimating the Dose to the Heart of a Male Adult-Reference-Cited by-同舟云学术

Program for Determining the Dosimetric Contribution of Tc-99m Biokinetics in Estimating the Dose to the Heart of a Male Adult

Published:2024-01 Issue:1 Volume:49 Page:1-5
ISSN:0971-6203
Container-title:Journal of Medical Physics
language:en
Short-container-title:

Author:

Morales-Nizama Rosa Adela¹,Gallozzo-Cárdenas Moisés Miguel²,Chinchay-Espino Héctor Almanzor¹,Murga-Torres Emzon³,Alvarez-Escobedo Amilu M.⁴,Nazario-Naveda Renny⁵

Affiliation:

1. Department of Science, Private University of the North, Chorrillos, Peru

2. School of Medicine, Cesar Vallejo University, Trujillo, Peru

3. Multidisciplinary Research Laboratory, Antenor Orrego Private University, Trujillo, Peru

4. Faculty of Health Sciences, Private University of the North, Trujillo, Peru

5. Vice Presidency of Research, Autonomous University of Peru, Lima, Peru

Abstract

Purpose: To calculate the contribution of absorbed dose by organs in the biokinetics of Tc-99m when used for radiodiagnosis of the adult male heart employing a Matlab program. Methods: The absorbed self-dose of the adult male heart and absorbed dose by organs in the biokinetics of the heart when administering Tc-99m are estimated using the MIRD formalism and the Cristy-Eckerman representation, which have been employed to develop the algorithm in Matlab. Results: The results indicate that electron capture emissions of 1.446 (mGy/MBq) and Auger electrons of 0.062 (mGy/MBq) are entirely directed towards the target organ (heart) and contribute 29.33% and 1.25% respectively to its total dose. Additionally, the dosimetric contributions of biokinetic organs correspond to characteristic radiation emissions and gamma photons at 2.578 (mGy/MBq) for Tc-99m, representing 52.29% of its total dose. Conclusion: These dosimetric contributions are significant in estimating the total absorbed dose by the heart in adult males and should not be disregarded.

Publisher

Medknow

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