Sample size calculation in clinical research

Author:

Ranganathan Priya1,Deo Vishal2,Pramesh C. S.3

Affiliation:

1. Department of Anaesthesiology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India

2. National Institute for Research in Digital Health and Data Science, Indian Council of Medical Research, New Delhi, India

3. Department of Surgical Oncology and Administration, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India

Abstract

Abstract Calculation of sample size is an essential part of research study design since it affects the reliability and feasibility of the research study. In this article, we look at the principles of sample size calculation for different types of research studies.

Publisher

Medknow

Reference20 articles.

1. Study designs: Part 2 – Descriptive studies;Aggarwal;Perspect Clin Res,2019

2. Study designs: Part 3 – Analytical observational studies;Ranganathan;Perspect Clin Res,2019

3. Study designs: Part 4 – Interventional studies;Aggarwal;Perspect Clin Res,2019

4. Equivalence trials;Ranganathan;Perspect Clin Res,2022

5. Non-inferiority trials;Ranganathan;Perspect Clin Res,2022

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