Eczema Coxsackium: An Unusual Manifestation of Hand, Foot, and Mouth Disease

Abstract

Eczema coxsackium is an atypical manifestation of hand, foot, and mouth disease (HFMD). It is a rare manifestation and can be easily mistaken for eczema herpeticum or impetigo. We report two male infants (twins) of 6 months of age who presented with 2 days of fever and diarrhea followed by an erythematous rash over the diaper region with multiple eroded papules. As the presentation coincided with a seasonal clustering of HFMD cases, eczema coxsackium was suspected. Polymerase chain reaction for pan-enteroviral RNA was positive in a throat swab, and a diagnosis of eczema coxsackium over the diaper dermatitis was made.