Management of migrated hyaluronic acid dermal filler with a delayed presentation

Author:

Garala Pavitra1,Awad John2,Vydianath Sanjay3,Mudhar Hardeep S4,Sandramouli Soupramanien1

Affiliation:

1. Wolverhampton Eye Infirmary, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, England

2. Leighton Hospital, Crewe, Cheshire, England

3. Department of Radiology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, England

4. Department of Histopathology, National Specialist Ophthalmic Pathology Service (NSOPS), Royal Hallamshire Hospital, Sheffield, England

Abstract

Hyaluronic acid (HA)-based dermal fillers are extremely popular among many seeking aesthetic treatment due to the short downtime and immediate results. Although HA is biodegradable, the body can still mount immune responses to this foreign body and molecules can persist in the system for longer than anticipated, resulting in complications months or years after the initial injection. We report a rare case of a 47-year-old Caucasian female who presented to us with bilateral lid swelling secondary to migration of her dermal filler and how she was successfully managed three years post administration with the injection of hyaluronidase along with histopathological results.

Publisher

Medknow

Subject

General Medicine

Reference10 articles.

1. Complications of injectable fillers, part I;DeLorenzi;Aesthet Surg J,2013

2. The degradation of hyaluronan in the skin;Žádníková;Biomolecules,2022

3. Periocular hyaluronic acid fillers: Applications, implications, complications;Murthy;Curr Opin Ophthalmol,2019

4. Effective rejuvenation with hyaluronic acid fillers: Current advanced concepts;Mckee;Plast Reconstruct Surg,2019

5. This month's guideline: The use of hyaluronidase in aesthetic practice (v2. 4);King;J Clin Aesthet Dermatol,2018

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