Bilateral recurrent choroidal neovascularization in AZOOR-Reference-Cited by-同舟云学术

Bilateral recurrent choroidal neovascularization in AZOOR

Published:2024-04 Issue:2 Volume:4 Page:477-480
ISSN:2772-3070
Container-title:Indian Journal of Ophthalmology - Case Reports
language:en
Short-container-title:

Author:

Sánchez-Quirós Julia¹,Galletero Lucía²,Giralt Lena³,Artaraz Joseba²,Ruiz-Arruza Ioana⁴,Soto Adriana⁴,Carreño Ester¹⁵,Fonollosa Alex²⁶

Affiliation:

1. Rey Juan Carlos University Hospital, Mostoles, Madrid, Spain

2. Department of Ophthalmology, Biocruces Bizkaia Health Research Institute, Cruces University Hospital, University of the Basque Country, Barakaldo, Spain

3. Clinic Institute of Ophthalmology, Hospital Clinic of Barcelona, Barcelona, Spain

4. Department of Internal Medicine, Biocruces Bizkaia Health Research Institute, Cruces University Hospital, University of the Basque Country, Barakaldo, Spain

5. Fundación Jiménez Díaz University Hospital, Madrid, Spain

6. Department of Retina, Instituto Oftalmológico Bilbao, Bilbao, Spain

Abstract

A 61-year-old man presented with recurrent bilateral peripapillary choroidal neovascularization (CNV), which was treated with intravitreal bevacizumab injections. Fundus autofluorescence revealed the typical acute zonal occult outer retinopathy (AZOOR) trizonal pattern, so the patient was started on immunosuppressive treatment with prednisone and methotrexate, and subsequently with mycophenolate mofetil due to recurrent inflammatory activity. While on immunosuppressive treatment, further CNV showing the “pitchfork sign” appeared in the right eye and required multiple bevacizumab injections due to persistent activity. The complication of CNV in AZOOR is very rare and treatment is a challenge. However, the combination of intravitreal anti-VEGF with immunosuppressive treatment could prevent the progression of the disease.

Publisher

Medknow

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