Kimura's disease of periocular region: Report of two cases and review of literature

Author:

Singh Manpreet1,Sharma Manjula1,Vaiphei Kim2,Kaur Manpreet1,Gupta Pankaj1

Affiliation:

1. Departments of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, India

2. Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Abstract

We report two patients with periocular Kimura's disease (KD). The clinical features and management of two histopathologically proven KD patients who underwent near-total mass excisions are discussed. Both were males (74 years and 55 years), having painless masses in the lacrimal sac region and upper eyelid, respectively. The masses were firm and adherent to surrounding tissues. Near-total mass excisions and histopathology showed dense germinal center hyperplasia with lympho-mononuclear infiltrates and skeletal muscle infiltration. Additional features of increased eosinophils and thin vessel vasculitis were suggestive of KD. Both were managed with oral steroids, and one recurrence with intralesional steroid injection, a novel treatment strategy for local recurrences in KD.

Publisher

Medknow

Subject

General Medicine

Reference18 articles.

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4. Simultaneous presentation of Kimura disease and angiolymphoid hyperplasia with eosinophilia;Esmaili;Ophthalmic Plast Reconstr Surg,2008

5. Kimura's disease of the lacrimal gland mimicking IgG4-related orbital disease;Li;BMC Ophthalmol,2014

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