Systemic lupus erythematosus (SLE) associated uveitis in India – A case series-Reference-Cited by-同舟云学术

Systemic lupus erythematosus (SLE) associated uveitis in India – A case series

Published:2023-12-15 Issue: Volume: Page:
ISSN:0301-4738
Container-title:Indian Journal of Ophthalmology
language:en
Short-container-title:

Author:

Magesan Kowsigan¹,Nangia Purna¹,Manoharan Anitha¹,Sitaula Ranju K²,Srikantiah Chandrashekara³,Biswas Jyotirmay¹

Affiliation:

1. Department of Uvea, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, Tamil Nadu, India

2. Department of Uvea, Uveitis Specialist, BPKLCOS, IOM, TU, Nepal

3. Department of Uvea, ChanRe Rheumatology and Immunology Center and Research, Bangalore, Karnataka, India

Abstract

Abstract Purpose: To report the uveitic manifestations of patients with systemic lupus erythematosus (SLE). Methods: This was a retrospective analysis of all SLE cases with ocular manifestations seen by a single ophthalmologist between 2015 and December 2021. Results: In total, seven patients with a median age of 40 (range 18–50) years were included in the study. Female (85.7%) predominance was noted. Ocular findings were bilateral in 71% (five patients) of cases. Majority (10 eyes, 83%) of the patients had retinal vasculitis as the common finding. Antinuclear antibodies were positive in all the patients. The vision improved in two (16.6%) eyes, was stable in eight (66%) eyes, and worsened in one (8%) eye. All the patients were treated with oral steroids along with immunosuppressive agents. Conclusion: Though SLE is rare cause of uveitis, it can be associated with significant ocular morbidity. Hence, early diagnosis and treatment can salvage vision in many cases.

Publisher

Medknow

Subject

Ophthalmology