Baclofen Toxicity in a Patient with End-stage Renal Disease on Maintenance Dialysis-Reference-Cited by-同舟云学术

Baclofen Toxicity in a Patient with End-stage Renal Disease on Maintenance Dialysis

Published:2023 Issue:1 Volume:34 Page:84-86
ISSN:1319-2442
Container-title:Saudi Journal of Kidney Diseases and Transplantation
language:en
Short-container-title:

Author:

Ahmed Samar¹,Kharrat Mahmoud²,Salah Hesham²,Shearyia Fouad²,Alrimawi Reem²,Makhsoom Azizah²,Al sharif Sahal²,Alyami Rozana²,Shaheen Faissal³

Affiliation:

1. Department of Nephrology, Suez Canal University, Ismailia, Egypt

2. Department of Nephrology, King Fahad Hospital, Jeddah, Saudi Arabia

3. Department of Nephrology, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia

Abstract

Baclofen is a β-(p-chlorophenyl) derivative of the neurotransmitter y-aminobutyrio acid (GABA). This centrally-acting GABA agonist is prescribed as therapy for spasticity in the spinal cord region. The drug is predominantly excreted by the kidney, thus making patients with kidney disease susceptible to side effects. We report on a patient with end-stage renal disease who developed baclofen toxicity, which was successfully treated with intense hemodialysis.

Publisher

Medknow

Subject

Nephrology,Transplantation

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