Immune Response to Respiratory Syncytial Virus

Author:

Alqirbi Hujaz Ismail Abdulrazzaq1,Mahdi Batool Mutar2,Almukhtar Mustafa3

Affiliation:

1. Department of Microbiology, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

2. Department of Microbiology, HLA Research Unit, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

3. Takhar’s Family Medicine and Urgent Care, Sacramento, CA, USA

Abstract

Abstract Respiratory syncytial virus (RSV) is an important cause of respiratory infection among children and infants globally. The first line of the immune response against this virus is neutrophils, macrophages, and innate lymphoid cells. Antigen-presenting cells such as dendritic cells which present the viral antigen to T lymphocytes that mediate viral clearance by T cytotoxic cells and initiate systemic lymphopenia. Humoral immunity will also be stimulated through B-cell-stimulating factors derived from epithelial cells of the respiratory tract that play an important factor in antibody production and induction memory to reinfection through IgG and IgA protective antibodies that are useful in vaccine production.

Publisher

Medknow

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