Affiliation:
1. Department of Nephrology, Apollomedics Superspeciality Hospital, Lucknow, Uttar Pradesh, India
Abstract
Dietary fibers are predominantly plant based carbohydrates which requires microbial activity for their breakdown in gut through anaerobic fermentation yielding short chain fatty acids. Despite being recognized as lacking nutritional values, Dietary fibers are considered important predominantly due to it's beneficial effects on blood pressure, glycemic control, lipid profile, body weight, inflammation and metabolic acidosis. Also, By modulation of gut dysbiosis secondary to diet-microbe-host interactions, It decreases uremic toxin production and it's permeability in chronic kidney disease patients. Due to these beneficial effects, Dietary fibers are considered to impact morbidity, progression of disease, decrease in cardiovascular complications leading to mortality in Chronic kidney disease patients. We are going to discuss the classification, dosing, beneficial effects, supporting evidences and recommendations pertaining to dietary fibers in chronic kidney disease in this article.