Do Asian Patients Require Only Half of the Clozapine Dose Prescribed for Caucasians? A Critical Overview

Author:

Leon Jose de12,Rajkumar Anto P.34,Kaithi Arun R.5,Schoretsanitis Georgios6,Kane John M.67,Wang Chuan-Yue8,Tang Yi-Lang9,Lin Shih-Ku10,Hong Kyung Sue11,Farooq Saeed12,Ng Chee H.13,Ruan Can-Jun14,Andrade Chittaranjan15

Affiliation:

1. Mental Health Research Center, Eastern State Hospital, Lexington, Kentucky, USA

2. Psychiatry and Neurosciences Research Group (CTS-549), Institute of Neurosciences, University of Granada, Granada, Spain, and Biomedical Research Centre in Mental Health Net (CIBERSAM), Santiago Apostol Hospital, University of the Basque Country, Vitoria, Spain

3. Department of Psychiatry, Christian Medical College, Vellore, Tamil Nadu, India

4. Institute of Mental Health, University of Nottingham, Nottingham, United Kingdom

5. Hazelwood Center, Louisville, Kentucky

6. Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks

7. Department of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA

8. Department of Psychiatry, The National Clinical Research Centre for Mental Disorders and Beijing Key Lab of Mental Disorders and Beijing Institute for Brain Disorders Center of Schizophrenia, Beijing Anding Hospital, Capital Medical University, Beijing, China

9. Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, and Substance Abuse Treatment Program, Atlanta VA Medical Center, Decatur, Georgia, USA

10. Department of General Psychiatry, Taipei City, Psychiatric Center, Taipei, Taiwan, and Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei, Taiwan

11. Department of Psychiatry, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea

12. School of Primary, Community and Social Care, Faulty of Medicine and Health Sciences, Keele University, Staffordshire, and Midlands Partnership NHS Foundation Trust, Staffordshire, United Kingdom

13. Department of Psychiatry, The Melbourne Clinic and St Vincent's Hospital, The University of Melbourne, Melbourne, Victoria, Australia

14. Laboratory of Clinical Psychopharmacology & The National Clinical Research Centre for Mental Disorders & Beijing Key Lab of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China

15. Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India

Publisher

SAGE Publications

Subject

Clinical Psychology,Psychiatry and Mental health

Reference50 articles.

1. Marder SR, Yang YS. Clozapine. In: Schatzberg AF, Nemeroff CB, editors. The American Psychiatric Association Publishing textbook of psychopharmacology. 5th edition. Washington, DC: American Psychiatric Association Publishing; 2017. p. 623-48.

2. Taylor DM, Barnes TR, Young AH. Maudsley Prescribing Guidelines in Psychiatry. 13th ed. Hosbroken, NJ: Wiley-Blackwell; 2018.

3. NICE. Psychosis and schizophrenia in adults: Prevention and management. Clinical guideline (nice.org.uk/guidance/cg178).

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