Ultrasound biomicroscopic findings in Fuchs uveitis syndrome: A contralateral eye study

Abstract

Abstract: PURPOSE: The aim of this study was to determine ultrasound biomicroscopic findings in patients with Fuchs uveitis syndrome (FUS). METHODS: This cross-sectional, contralateral comparative eye study was conducted on patients with unilateral FUS. Both eyes of each patient underwent ultrasound biomicroscopy (UBM) imaging at the 12, 3, 6, and 9-o’clock radial meridians. Ultrasonographic data were collected, including the thickness (mm) of the ciliary body (CB), CB with ciliary processes, and iris thickness at 0.8 mm from the iris root, mid-iris, and iris tip. RESULTS: We enrolled 36 eyes from 18 patients with unilateral FUS, including 10 (55.6%) females, with a mean age of 38.44 ± 9.2 years. The average thickness of CB (P < 0.001), 0.8 mm from the iris root (P = 0.003), mid-iris (P < 0.001), and the iris tip (P < 0.001) was thinner in the affected eyes compared to the fellow eyes of the patients. Analysis of variance analysis showed that differences among all quadrants were not significant in both groups (P > 0.05). CONCLUSION: This study showed that CB and iris thickness were significantly thinner in the affected eyes compared to the fellow eyes of patients with FUS, as assessed using the UBM technique.