Oxaliplatin-induced papilledema: Rare case report

Abstract

Papilledema is the presence of bilateral optic disc edema in the presence of raised intracranial pressure and often is symmetric. We report a case of a 70-year-old male with rectal carcinoma on chemotherapy presented with minimal drop in visual acuity. The patient has bilateral disc edema and investigations including computed tomography and cerebrospinal fluid opening pressure were normal and no evidence of brain metastasis has been found. The patient was on oxaliplatin regimen and literature search has shown very few cases of platinum chemotherapy agents-induced papilledema. So far to our knowledge, oxaliplatin-induced papilledema has not been reported and knowing this condition can be sight saving for ill patients.