Fibrillary Glomerulonephritis with Prevalent IgA Deposition Associated with Psoriasis

Author:

Patel Sujit1,Patel Himanshu1,Kunpara Janmejay1,Bhalodiya Ronak1,Shah Jainam1,Patwari Devang1,Darji Prakash1

Affiliation:

1. Department of Nephrology, Zydus Hospital, Ahmedabad, Gujarat, India

Abstract

Abstract Fibrillary and immunotactoid glomerulonephritis represent the pathological entities characterized by structured fibrillary/microtubular deposits, whose identification is possible only by electron microscopy. We report a 46-year-old female who presented with proteinuria 15 years after the onset of psoriasis. Diffuse global glomerulosclerosis pattern was noted on light microscopy. In immunofluorescence microscopy, predominant IgA deposition was observed and electron microscopy showed organized randomly arranged fibrillary deposits with diameter ranging between 10 and 23 nm in mesangial, subendothelial, intramembranous, and subepithelial sites.

Publisher

Medknow

Subject

Nephrology

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