From Alpha to Omicron Genetic Variants: The Evolution of Severe Acute Respiratory Syndrome Coronavirus 2 and Other Beta Coronaviruses – A Narrative Overview from Public Health Point of View

Author:

Harisingani Avi1,Gupta Nikita2,Pustake Manas23,Ganiyani Mohammad Arfat23,Shahnaz Fathima4,Shah Aditya2,Shah Priyanshi5,Mukherjee Sayan2,Deshmukh Krishna2

Affiliation:

1. Department of Internal Medicine, Loyola MacNeal Hospital, Berwyn, IL, USA

2. Department of Internal Medicine, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, Maharashtra, India

3. Harvard Medical School, Harvard University, Boston, MA, USA

4. Department of Internal Medicine, Trinity Health Oakland/ Wayne State University, Mumbai, India

5. Department of Internal Medicine, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India

Abstract

Acute respiratory syndrome coronavirus disease-2019, caused by a new coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) with a high morbidity and death rate, has emerged as one of humanity’s most serious dangers in recent decades. Because of the virus’s ongoing development, with its single-nucleotide polymorphism variations and many lineages, determining SARS-CoV-2 infectivity is very challenging. However, it is critical to do in-depth research on the virus to understand the mechanisms of its pathogenicity and virulence and to create efficient treatment methods. The current contribution compiles existing information on the virus’s evolutionary and structural characteristics to explain its mutational pattern and potential involvement in the ongoing epidemic.

Publisher

Medknow

Reference40 articles.

1. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia;Li;N Engl J Med,2020

2. Anovel coronavirus from patients with pneumonia in China, 2019;Zhu;N Engl J Med,2020

3. Severe acute respiratory syndrome-related coronavirus: The species and its viruses –A statement of the coronavirus study group;Gorbalenya;bioRxiv,2020

4. SARS: Epidemiology;Chan-Yeung;Respirology,2003

5. Hospital outbreak of Middle East respiratory syndrome coronavirus;Assiri;N Engl J Med,2013

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