Amyloid-beta pathology–induced nanoscale synaptic disruption: the case of the GABAB

Amyloid-beta pathology–induced nanoscale synaptic disruption: the case of the GABAB–GIRK assembly

Published:2024-06-26 Issue:5 Volume:20 Page:1409-1410
ISSN:1673-5374
Container-title:Neural Regeneration Research
language:en
Short-container-title:

Author:

Luján Rafael¹^ORCID,Martín-Belmonte Alejandro¹,Ferré Sergi²,Ciruela Francisco³^ORCID

Affiliation:

1. Synaptic Structure Laboratory, Instituto de Biomedicina de la UCLM (IB-UCLM), Departamento de Ciencias Médicas, Instituto de Investigación en Salud de Castilla-La Mancha (IDISCAM), Facultad de Medicina, Universidad Castilla-La Mancha, Campus Biosanitario, C/ Almansa, Albacete, Spain (Luján R, Martín-Belmonte A)

2. Integrative Neurobiology Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA (Ferré S)

3. Pharmacology Unit, Department of Pathology and Experimental Therapeutics, School of Medicine and Health Sciences, Institute of Neurosciences, University of Barcelona, Neuropharmacology & Pain Group, Neuroscience Program, Bellvitge Institute for Biomedical Research, L’Hospitalet de Llobregat, Spain (Ciruela F)

Publisher

Medknow

Reference11 articles.

1. G protein-coupled receptor-G protein interactions: a single-molecule perspective;Calebiro;Physiol Rev,2021

2. G protein-coupled receptor-effector macromolecular membrane assemblies (GEMMAs);Ferré;Pharmacol Ther,2022

3. Regulation of neuronal GABA(B) receptor functions by subunit composition;Gassmann;Nat Rev Neurosci,2012

4. SK2 channels associate with mGlu1α receptors and CaV2.1 channels in Purkinje cells;Luján;Front Cell Neurosci,2018

5. Differential association of GABAB receptors with their effector ion channels in Purkinje cells;Luján;Brain Struct Funct,2018