Total laparoscopic curative resection of a rare pan-necrotic solid pseudopapillary pancreatic tumor in a child

Abstract

Abstract: Tumor necrosis is purportedly related to an aggressive tumor phenotype in few solid tumors such as pancreatic ductal carcinoma, breast and bladder carcinomas. We hereby report a unique pan-necrotic (98% of tumor) pseudopapillary pancreatic tumor in a 13-year-old child who underwent laparoscopic subtotal pancreatectomy and curative resection. To our knowledge, this is the first account of complete tumor necrosis in a pancreatic neoplasm with curative laparoscopic resection. This case report has discussed the literary background of various mechanisms of cell death in solid tumors to explain the plausible cause of unique pan-tumor necrosis.