IADVL SIG Recalcitrant Dermatophytosis Position Statement on Super Bioavailable Itraconazole

Author:

Patel Nayankumar H.1,Sardana Kabir2,Shenoy Manjunath M.3,Rengasamy Madhu4,Khurana Ananta2,Ghate Sunil5,Venkata Chalam Konakanchi6,Marfatiya Yogesh7,Bhunia Deblina8,Jayaraman Jyothi9,Das Anupam10,Jain Akshay Kumar11

Affiliation:

1. Department of DVL, GCS Medical College Hospital and Research Centre, Ahmedabad, Gujarat, India

2. Department of Dermatology, Dr. Ram Manohar Lohia Hospital and Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, India

3. Department of DVL, Yenepoya Medical College, Mangalore, Karnataka, India

4. Department of DVL, Madras Medical College, Chennai, Tamil Nadu, India

5. Dr. Ghate’s Skin, Hair and LASER Centre, Mumbai, Maharashtra, India

6. Government Medical College, Srikakulam, Andhra Pradesh, India

7. SBKS MI and RC, Piparia, Waghodia, Vadodara, Gujarat, India

8. M.G.M. Medical College, Kishanganj, Bihar, India

9. Department of Dermatology, Father Muller Medical College, Manglore, Karnataka, India

10. Department of DVL, KPC Medical College and Hospital, Kolkata, West Bengal, India

11. GMC, Kota, Rajasthan, India

Abstract

Abstract Itraconazole (ITZ) has been the mainstay of oral antifungal treatment for the current epidemic of recalcitrant dermatophytosis (RD) in India. Recently, a newer formulation of ITZ, super bioavailable itraconazole (SUBA-ITZ), is made available in the market by many pharmaceutical companies. It is important for dermatologists to understand the pharmacokinetic properties of SUBA-ITZ vis-a-vis conventional pellet formulation to use it effectively and safely. Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) has established a special interest group for recalcitrant dermatophytosis (SIG-RD) to strengthen research, continuing medical education, and industry collaboration on the subject. This position statement on SUBA-ITZ by SIG-RD is an attempt to address current pieces of evidence and the position of this new formulation in the management of RD.

Publisher

Medknow

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