Abstract
Today, tuberculosis (TB) kills one person in 14 s in India and one in 12 s, worldwide (that comes to approximate 4000 people per day). The majority of cases are invisible because they are either confined in sanatoria and/or do not encumber regular hospitalization, in contrast to SARS-CoV-2 (COVID-19) pandemic. The COVID-19 pandemy has put in glaring light the fragility of the elders, the minorities, and the exposure of the healthcare agents that was similar to Mycobacterium tuberculosis infection. The mayhem of coronavirus might be repeated itself with the foreseen rise of TB, that would affect the healthcare system resemble much of what occurred during the last 3 years (2019-till date). We must keep in mind that currently TB is neglected and that it might expand again, due to the COVID-19 pandemic. In this review, the past and further perspective of Bacille Calmette–Guérin (BCG) vaccination is described. In addition, the tuberculin skin-testing which has a complex and long story was reviewed. Furthermore, the effect and side-effect of BCG vaccination compared and discussed.
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