Efficacy and Clinical Predictors of Response to Repetitive Transcranial Magnetic Stimulation Treatment in Resistant Obsessive-compulsive Disorder

Abstract

Deep transcranial magnetic stimulation has been effectively used as a therapy for refractory obsessive compulsive disorder (OCD). Number of sessions approved by FDA is 20. Here, we report the case of 59 year old female with treatment refractory obsessive compulsive disorder (OCD) whose symptoms markedly improved only after 10 sessions of deep TMS over Dorso Medial Prefrontal Cortex. Our case report shows that, even with fewer sessions than indicated, significant symptoms remission can be achieved with deeper penetration of magnetic field with marked reduction in distress of patient and significant improvement in socio-occupational domain. Her Y-BOCS score reduced by 66% at the end of 10 completed sessions.