Plasmocitoma/multiple myeloma with severe cord compression: Case reports

Abstract

Abstract Introduction: Multiple myeloma (MM) is generally located in the bone marrow (BM) and is associated with a wide spectrum of clinical, laboratory, and radiological findings.[1] Conversely, solitary plasmacytoma (SP) is characterized by a single mass of clonal plasma cells, with no or minimal BM plasmacytosis and with no other symptoms than those derived from the primary lesion.[2] The cases with spine involvement and spine cord suffering from compression always were very complicated and challenging. Materials and Methods: We describe two cases of SP and MM with severe spine cord compression treated surgically with an indication to address the compression and stabilization of the affected segments with subsequent treatment in hematology and oncology. Results: In both cases, the surgery was a success, the patient with SP survived 3 years and 1 month, and the patient with MM survived 1 year and 3 months. Conclusion: The outcomes of surgical interventions for these patients with spine cord compression and spinal instability due to MM and plasmacytoma of the spine were improved with neurological function following surgery and no instrumentation failure.