Prevalence profile of cutaneous T- and B-cell lymphoma in Gharbia Governorate, Egypt

Abstract

Background Lymphomas represent a heterogeneous group of lymphoid malignancies with varied patterns of clinical behavior and responses to treatment. The WHO classification distinguishes lymphoid neoplasms derived from precursor lymphoid cells from those derived from mature lymphoid cells and separates each group into neoplasms of B-cell or T-cell origin. T-cell lymphomas represent 82.9%, while B-cell lymphomas account for 21.3% of cutaneous lymphomas. Objective To study the prevalence of cutaneous T- and B-cell lymphomas in Gharbia Governorate, Egypt from 1999 to 2019. Patients and methods This descriptive, retrospective study was based on the records of patients clinically and pathologically diagnosed with T- and B-cell lymphoma from 1999 to 2019 and registered in registry unit of Tanta Cancer Center and the outpatient clinic of Department of Dermatology and Venereology, Tanta University. Results The prevalence rate of cutaneous T-cell lymphoma was 3.04 P/m population, with a male-to-female ratio of 1 : 1.15, while the prevalence of B-cell lymphoma was 0.63 P/m population, with a male–to-female ratio of 1.4 : 1 in Gharbia Governorate, Egypt at the end of the study. The highest prevalence rate of T- and B-cell lymphoma (2430 P/m population) was recorded in the age group of over 80 years and the least prevalence rate (21.25 P/m population) was recorded in the age group of 10–20 years. Conclusion T-cell lymphoma was more common than B-cell lymphoma, both are diseases of the older age group, and there was no sex predilection for T-cell lymphoma distribution and a slight elevation of male ratio in B-cell lymphoma distribution.