Destructive cervical spine disease with concomitant chronic myeloid leukemia: A case report

Abstract

ABSTRACT A significant majority of patients with chronic myeloid leukemia (CML) present with chronic-phase disease and demonstrate an excellent long-term response to therapy. However, for patients presenting with advanced-phase disease, treatment modification in the form of second-line tyrosine kinase inhibitors (TKIs) or chemotherapy with allogeneic stem cell transplantation is indicated. To add to the literature, we report a patient who presented with atypical features with destructive cervical spine lesions, which required rapid assessment and surgical fixation to determine the disease stage and initiate appropriate therapy.