Ewing's sarcoma of rib presenting as pleural effusion in a young child

Author:

Bisen Pratima1,Kavishwar Madhura1,Wade Poonam1,Khandkar Omkar2,Balasubramanian Meenakshi3

Affiliation:

1. Department of Pediatrics, Topiwala National Medical College and B. Y. L. Nair Ch Hospital, Mumbai, Maharashtra, India

2. Department of Medical Oncology, Topiwala National Medical College and B. Y. L. Nair Ch Hospital, Mumbai, Maharashtra, India

3. Department of Pathology, Topiwala National Medical College and B. Y. L. Nair Ch Hospital, Mumbai, Maharashtra, India

Abstract

Ewing's sarcoma of rib is a rare primary malignant bone tumour which poses diagnostic dilemma and has complex treatment. The diagnosis is based on the combination of clinical, imaging, pathology and immunohistochemistry findings. We here present a case of 3.5 years old male child who presented acutely with the complaints of fever, cough and breathlessness mimicking the diagnosis of pneumonia. Massive right-side pleural effusion was seen on chest radiograph. Further radiological investigation of high-resolution contrast computed tomography (HRCT) and Positron emission tomography (PET) scan along with biopsy and immunohistochemistry lead to the diagnosis of Ewing's sarcoma arising from right rib. Patient was treated with chemotherapy, and there was significant reduction in lesion, along with clinical improvement in symptoms.

Publisher

Medknow

Subject

Pulmonary and Respiratory Medicine

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5. Changes in incidence and survival of Ewing sarcoma patients over the past 3 decades: Surveillance Epidemiology and End Results data;Esiashvili;Journal of pediatric hematology/oncology,2008

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