The effects and potential of microglial polarization and crosstalk with other cells of the central nervous system in the treatment of Alzheimer’s disease

Author:

Ma Cun-Gen,Wu Yi-Ge,Song Li-Juan,Yin Li-Jun,Yin Jun-Jun,Wang Qing,Yu Jie-Zhong,Xiao Bao-Guo

Publisher

Medknow

Subject

Developmental Neuroscience

Reference189 articles.

1. Ahn JW, Jang SK, Jo BR, Kim HS, Park JY, Park HY, Yoo YM, Joo SS (2021) A therapeutic intervention for Alzheimer’s disease using ginsenoside Rg3: its role in M2 microglial activation and non-amyloidogenesis. J Physiol Pharmacol doi: 10.26402/jpp.2021.2.04.

2. Alexandrov PN, Zhao Y, Jones BM, Bhattacharjee S, Lukiw WJ (2013) Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell line. J Inorg Biochem 128:267-269.

3. Anwar S, Rivest S (2020) Alzheimer’s disease: microglia targets and their modulation to promote amyloid phagocytosis and mitigate neuroinflammation. Expert Opin Ther Targets 24:331-344.

4. Arranz AM, De Strooper B (2019) The role of astroglia in Alzheimer’s disease: pathophysiology and clinical implications. Lancet Neurol 18:406-414.

5. Ashtari F, Madanian R, Shaygannejad V, Zarkesh SH, Ghadimi K (2019) Serum levels of IL-6 and IL-17 in multiple sclerosis, neuromyelitis optica patients and healthy subjects. Int J Physiol Pathophysiol Pharmacol 11:267-273.

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