Squamous Cell Carcinoma Developing De Novo in an Untreated, Nonsun-Exposed Psoriatic Plaque

Author:

Tandon Sidharth1,Sharma Prafulla Kumar1,Zutso Kezhaleto1,Singh Ajeet1

Affiliation:

1. Department of Dermatology, Venereology and Leprosy, Postgraduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, India

Abstract

AbstractPsoriasis is a chronic inflammatory dermatosis, which causes hyperproliferation of skin. Patients afflicted with psoriasis are also at a risk of developing nonmelanoma skin cancers, with the risk of such a possibility being attributed to the administration of systemic immunosuppressive agents, phototherapy, and biological agents. We present a case of psoriasis with de novo development of squamous cell carcinoma, in a photoprotected site, with no history of administration of systemic immunosuppressive agents, phototherapy, or biological agents.

Publisher

Georg Thieme Verlag KG

Subject

Oncology,Pediatrics, Perinatology and Child Health

Reference10 articles.

1. Malignant tumours and psoriasis: A follow-up study;G Frentz;Br J Dermatol,1999

2. Risk of malignancies in psoriasis patients treated with cyclosporine: A 5 y cohort study;C F Paul;J Invest Dermatol,2003

3. Squamous cell carcinoma: A review of etiology, pathogenesis, treatment, and variants;R M Shulstad;J Dermatol Nurs Assoc,2010

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