Deluging Thrombosis: An Unusual Presentation of Acute Promyelocytic Leukemia

Author:

Jandial Aditya1,Mishra Kundan1,Lad Deepesh1,Naseem Shano2,Malhotra Pankaj1

Affiliation:

1. Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India

2. Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Abstract

AbstractAcute promyelocytic leukemia (APML) patients are prone to thrombosis. However, thrombosis at presentation is rare in APML. Our patient presented with thrombosis and cytopenia, and the clinical diagnosis was of paroxysmal nocturnal hemoglobinuria. However, subsequent peripheral blood smear and bone marrow study confirmed the diagnosis of APML. The patient was successfully managed with anticoagulation, arsenic trioxide, and all-trans retinoic acid.

Publisher

Georg Thieme Verlag KG

Subject

Oncology,Pediatrics, Perinatology and Child Health

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