Expression of Calretinin Expression in Odontogenic Cysts and Odontogenic Tumors – Original Research-Reference-Cited by-同舟云学术

Expression of Calretinin Expression in Odontogenic Cysts and Odontogenic Tumors – Original Research

Published:2024-02 Issue:Suppl 1 Volume:16 Page:S227-S229
ISSN:0976-4879
Container-title:Journal of Pharmacy and Bioallied Sciences
language:en
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Author:

Pabbaraju Srinivasulu¹,Boddeda Kondala R.²,Sankurathree Sravani³,Menon Ipseeta⁴,Rai Narendra P.⁵,Nagella Sai P.⁶

Affiliation:

1. Department of Oral and Maxillofacial Surgery, Adhiparasakthi Dental College and Hospital, Melmaruvathur, Tamil Nadu, India

2. Department of Pedodontics and Preventive Dentistry, KIMS Dental College and Hospital, Amalapuram, Andhra Pradesh, India

3. KIMS Dental College and Hospital, Amalapuram, Andhra Pradesh, India

4. Department of Public Health Dentistry, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India

5. Faculty of Dentistry, MAHSA University, Malaysia

6. Department of Pediatric Dentistry, Faculty of Dentistry, MAHSA University, Selangor, Malaysia

Abstract

ABSTRACT Aim: The present study was conducted for assessing variability in calretinin expression among odontogenic cysts as well as tumor cases. Materials and Methods: Fifteen cases were included in the present research consisting of cases like – dentigerous cyst, odontogenic keratocyst, apical radicular cyst along with tumors like ameloblastoma, ameloblastic carcinoma, adenomatoid odontogenic tumor. Calretinin antibody was used for immunohistochemical staining. The amount of expression of this calretinin was statistically analyzed with the help of Chi-square test where P < 0.05 was considered noteworthy statistically. Results: Most cases of ameloblastomas were highly positive for calretinin expression as compared to other cysts and tumors. Therefore, the correlation of this variation of expression of calretinin was statistically noteworthy (P = 0.00). Conclusion: In this study, we concluded that for ameloblastomas, calretinin can be a specific marker immunohistochemically and can help in identifying the amount of aggressive spread of various odontogenic tumors.

Publisher

Medknow

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