A Retrospective Analysis of Salivary Gland Tumor Cases: Histological Variations and Clinical Outcomes

Author:

Dolma Kunzes1,Issac Anu Sumi2,Gupta Renuka3,Achanta Surya Kumari4,Channe Pallavi P.5,Ramanand Oruganti Venkata6,Managutti Anil7

Affiliation:

1. Department of ENT, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India

2. Department of Pathology, Dr Somervell Memorial CSI Medical College, Karakonam, Trivandrum, Kerala, India

3. Department of Oral Pathology and Microbiology, Teerthankar Mahaveer Dental College and Research Centre, Moradabad, Uttar Pradesh, India

4. BDS, Gitam Dental College and Hospital, Visakhapatnam, Andhra Pradesh, India

5. Department of Oral Medicine and Radiology, Dr. DY Patil Dental College, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra, India

6. Department of Oral and Maxillofacial Pathology, Nimra Institute of Dental Sciences, Ibrahimpatnam, Vijayawada, Andhra Pradesh, India

7. Department of OMFS, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India

Abstract

ABSTRACT Background: Salivary gland tumors (SGTs) present a diagnostic challenge due to their diverse histological subtypes and variable clinical behavior. Methods: This research conducted a retrospective analysis of SGT cases diagnosed and managed at a tertiary care center between 2017 and 2022. Clinical and pathological data were retrieved from medical records and histopathology reports. Statistical analysis was performed to identify factors associated with recurrence and survival outcomes. Results: A total of 150 SGT cases were included, comprising 70% benign and 30% malignant tumors. Pleomorphic adenoma and adenoid cystic carcinoma were the most prevalent benign and malignant subtypes, respectively. Surgical resection was the primary treatment modality, with varying recurrence rates observed among different treatment groups. Conclusion: The current study provides insights into the histological variations and clinical outcomes of SGTs. Surgical resection remains the mainstay of treatment, with adjuvant therapy reserved for cases with adverse prognostic factors. Further research is needed to optimize therapeutic strategies and improve patient outcomes.

Publisher

Medknow

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