To Assess the Serum and Salivary Biomarkers in People with and Without Diabetes

Author:

Sidhu Gagandeep K.1,Sidhu Sandeep1,Singh Harkanwal P.2,Gandhi Piyush2,Sidhu Jaskirat3,Kathuria Navneet S.1

Affiliation:

1. Department of Oral Pathology and Microbiology, Maharaja Ganga Singh Dental College and Research Centre, Sriganganagar, Rajasthan, India

2. Department of Oral Pathology and Microbiology, Dasmesh Institute of Research and Dental Sciences, Faridkot, Punjab, India

3. Department of Periodontology, Maharaja Ganga Singh Dental College and Research Centre, Sriganganagar, Rajasthan, India

Abstract

ABSTRACT The study was conducted to assess the serum and salivary biomarkers in people with and without diabetes. Among the 100 participants in this cross-sectional comparative study, 59 men and 61 women aged 32 to 59 years old were randomly assigned to category I (consisting of 50 diabetes mellitus (DM) patients of both types 1 and 2) or category II (consisting of 50 healthy volunteers) to serve as comparisons. Since there is no difference in the amounts of salivary biomarkers across the various types of diabetes, they are all grouped together. Several biochemical indicators were measured by measuring the amounts in the participants’ saliva and serum samples. There was little to no difference between the two categories when comparing saliva and serum levels. Although there was a strong correlation between serum and salivary glucose, amylase, total proteins, albumin, and globulin levels in DM patients, there was also a strong correlation between diabetics and non-diabetics for these same markers.

Publisher

Medknow

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,Bioengineering,General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,Bioengineering

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