Retrospective Review of Treatment Outcomes in Epilepsy Patients: Seizure Control and Medication Side Effects

Author:

Naveen P1,Sarala G1,Chandra D. Manoj2,Dutta Riddhiman3,Satodiya Vimal4,Imran Rangraze5,Pandey Pritee Rajkumar6

Affiliation:

1. Department of Neurology, Meenakshi Medical College Hospital and Research Institute, Kanchipuram, Tamil Nadu, India

2. Department of Neurosurgery, Yashoda Superspeciality Hospital, Secunderabad, Telangana, India

3. Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Bhubaneshwar, Odisha, India

4. Consultant, Inland Psychiatric Medical Group, Redlands, California, USA

5. Department of Internal Medicine, RAK Medical and Health Sciences University, Ras Al-Khaimah, United Arab Emirates

6. Consultant and MD, Oral and MaxilloFacial Surgeon, Dr Pritee’s Polyclinic, Navi Mumbai, Maharashtra, India

Abstract

ABSTRACT Background: Epilepsy management requires balancing seizure control with minimizing medication side effects. This retrospective review examines treatment outcomes in epilepsy patients, focusing on seizure control and medication-related adverse effects. Methods: Medical records of epilepsy subjects treated tertiary care center between 2017 and 2022 were retrospectively reviewed. Data on demographic characteristics, seizure control, medication regimen, and side effects were collected and analyzed. Results: A total of 200 subjects were included. Sixty percent of subjects achieved total seizure independence, 30% reduced seizure frequency, and 10% did not improve or deteriorate. The kind of antiepileptic medicine provided substantially affects prescription side effects (P < 0.05), with drug X causing more dizziness than drug Y (P = 0.02). Elderly individuals were more likely to suffer weariness than younger ones (P = 0.03). Conclusion: This review provides valuable insights into epilepsy treatment outcomes, emphasizing the need for personalized management strategies to optimize seizure control while minimizing medication-related adverse effects.

Publisher

Medknow

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