A comprehensive review on combination of lobeglitazone and glimepiride in management of type 2 diabetes mellitus

Abstract

Type 2 diabetes mellitus (T2DM) is a prevalent chronic condition with increasing global incidence, necessitating effective and well-tolerated treatment options. In recent years, the combination of lobeglitazone sulfate and glimepiride has emerged as a promising therapeutic approach. Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus who are already treated with a thiazolidinedione and sulphonylurea or who have inadequate glycemic control on a thiazolidinedione alone or a sulphonylurea alone. This review aims to comprehensively evaluate the efficacy and safety of lobeglitazone sulfate + glimepiride tablets in the management of T2DM.