Author:
John Sujith Mathew,Sagar Sheeba,Aparna Joshi Krishnakumari,Joy Sharon,Mishra Ajay Kumar
Abstract
Background:
Tuberculosis (TB) is prevalent worldwide and causes significant morbidity and mortality. TB is known to cause hypercalcemia. We aimed to assess the prevalence and risk factors for developing hypercalcemia among patients with TB.
Methods:
In this retrospective case–control study, patients with microbiological evidence of TB and an available serum calcium value were included between 2005 and 2016. The demographic, clinical, and laboratory details were recorded. Various risk factors were compared in TB patients with and without hypercalcemia.
Results:
A total of 129 patients fulfilled the inclusion criteria. Twenty percent were found to have an elevated serum calcium level, 65% of them had clinical features of hypercalcemia. In comparison, the odds of developing hypercalcemia in the presence of disseminated TB, diabetes and renal failure was 1.83, 1.60, and 7.33, respectively.
Conclusion:
One-fifth of patients with TB have hypercalcemia. Risk factors of the same are renal failure, diabetes, and disseminated TB.
Reference23 articles.
1. Latent tuberculosis infection treatment initiation and completion rates in persons seeking immigration and healthcare workers;Lal;Am J Med,2019
2. Severe hypercalcemia in a patient with pulmonary tuberculosis;Rajendra;J Family Med Prim Care,2016
3. Hypercalcemia in active pulmonary tuberculosis;Abbasi;Ann Intern Med,1979
4. Low incidence of hypercalcaemia in tuberculosis in Malaysia;Tan;J Trop Med Hyg,1993
5. Hypercalcemia and acute pancreatitis in a male patient with acute promyelocytic leukemia and pulmonary tuberculosis;Abdullah;Acta Biomed,2018
Cited by
11 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献